PARTICLE-MEDIATED INTRAVENOUS DELIVERY OF ANTIGEN MRNA RESULTS IN STRONG ANTIGEN-SPECIFIC T-CELL RESPONSES DESPITE THE INDUCTION OF TYPE I INTERFERON

Cancer vaccines based on mRNA are extensively studied.The fragile nature of mRNA has instigated research into carriers that can protect it from ribonucleases and as such enable its systemic use.However, copyright-mediated delivery of mRNA has been linked to production of type I interferon (IFN) that was reported to compromise the effectiveness of m

The community considers that fiqh in pesantren is lagging, so it cannot answer the issues that are rampant in the current era.Most of them consider that fiqh is an instant and final legal product that does not need to be reinterpreted several times.The attempt to provide a re-understanding of the fiqh of the past has experienced a deadlock because

A case of umbilical pemphigus vulgaris is Paskowitz reported.A 37-year-old female presented with a half-year history of repeated oral blood blisters and periumbilical itchy blisters.Dermatological examination revealed a demarcated annular irregular erosive surface covered with odorless white secretions on the umbilical area.But neither blisters nor